Test of donor immune cells after stem cell transplant to prevent relapse
Part of Blood & lymphatic, Cancer clinical trials.
This early-phase study tests a modified immune-cell treatment given after a haploidentical stem cell transplant (using a half-matched donor). It aims to reduce the immune attack complications while still helping prevent or control blood cancer return.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a blood cancer diagnosis (AML, ALL, Hodgkin’s, non-Hodgkin’s lymphoma, MDS/MPS, or multiple myeloma).
- Your cancer is in remission or stable disease, or has relapsed/refractory disease (not steadily worsening right before transplant).
- You must be age 8 weeks to 65 years at the right time for screening.
- You must be at least 3 months out from your most recent stem cell transplant, and have not had one in the prior 8 weeks.
- You cannot have certain recent immune/IL-2 medicines (like alemtuzumab or basiliximab) in the past 60 days.
- You must not have serious ongoing organ/brain/lung infections or major heart/kidney/liver limits that would make transplant unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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