Clin2
NCT05955924Possibly a fitRecruiting

Nicotinamide to prevent skin cancer after organ transplant

Non-melanoma Skin CancerCarcinoma, Squamous CellCarcinoma, Basal CellKeratinocyte Carcinoma

Treatments studied

Part of Cancer clinical trials.

This trial tests nicotinamide (a vitamin-like medicine) to help prevent new keratinocyte skin cancers in people who have had a kidney, liver, heart, or lung transplant. It may lower the chance of developing new skin tumors while you continue your usual transplant anti-rejection medicines.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
396 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You had a kidney, liver, heart, or lung transplant at least 2 years ago
  • You have had at least one prior skin cancer of the keratinocyte type (or squamous cell carcinoma in situ), confirmed by biopsy
  • You take anti-rejection medicine that includes tacrolimus or cyclosporine
  • You can come to follow-up visits during the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07286318Recruiting· Early Phase 1
Niacinamide cream for skin cancer prevention in transplant patients

This trial tests if a daily cream with 5% niacinamide (a form of vitamin B3) can help prevent skin cancer in people who have had an organ transplant. You will apply the cream to your skin and also use sunscreen every day.

Pittsburgh, Pennsylvania
NCT05702398Recruiting· Early Phase 1
Vitamin A and niacinamide for high-risk skin cancer

This early trial tests whether adding vitamin A and niacinamide (a form of vitamin B3) can help people with a history of certain skin cancers reduce new disease. It is designed for adults with specific prior skin cancer or skin lesion treatment patterns.

Providence, Rhode Island
NCT04844528Recruiting· Phase 2
Nicotinamide for CLL patients with recent skin cancer history

This Phase 2 trial tests whether nicotinamide (a form of vitamin B3) can help people with chronic lymphocytic leukemia (CLL) who have had non-melanoma skin cancers in the past 5 years. The study looks at how well new skin cancers can be prevented or reduced.

Salt Lake City, Utah
NCT05896839Recruiting· Phase 1/Phase 2
Immunotherapy with prednisone and sirolimus for transplant skin cancer

This early-phase study tests whether adding immunotherapy (nivolumab and ipilimumab) to prednisone and sirolimus can control advanced skin cancers in people with kidney transplants. It aims to see how well the treatment works and how safe it is for transplant recipients.

La Jolla, California
NCT05732051Recruiting· Phase 2
Nicotinamide riboside to protect the heart during breast cancer chemo

This trial tests whether nicotinamide riboside can help prevent heart problems caused by a common breast-cancer chemotherapy (anthracyclines). If you’re eligible, you’ll be followed to see how your heart is doing during treatment.

Lørenskog, Akershus
NCT04204837Recruiting· Phase 2
Nivolumab for advanced skin squamous cell cancer

This trial studies nivolumab, an immune therapy, for skin squamous cell cancer that can’t be cured with surgery or radiation. It aims to see how well the treatment shrinks tumors and helps people live longer or longer without cancer growth.

Graz

Hear when a new Non-Melanoma Skin Cancer (NMSC) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.