Treatment
Nicotinamide clinical trials
We’re tracking 51 recruiting studies that include Nicotinamide, each written for real people, not researchers, below.
Recruiting studies
- NCT06991712RecruitingPhase 2
NAD supplements for nerve health in glaucoma
This trial tests whether NAD precursor supplements can improve nerve health and vision in people with glaucoma. If you have glaucoma with mild to moderate vision loss, this study may help understand if these supplements could protect your optic nerve.
Wong Chuk HangAges 18 years+ - NCT06731582Enrolling by invitationPhase 3
Nicotinamide supplement study for glaucoma patients
This trial tests whether a vitamin B3 supplement called nicotinamide can help slow down vision loss in people with glaucoma. It is for those with moderate disease who are already on treatment.
Singapore, Central SingaporeAges 21 years+ - NCT06599918RecruitingPhase 2
Nicotinamide for liver scarring in fatty liver disease
This study tests whether nicotinamide (a form of vitamin B3) can help reduce liver scarring in people with nonalcoholic fatty liver disease. You may qualify if you have moderate to severe liver scarring and are between 18 and 85 years old.
BarcelonaAges 18–85 - NCT06567717RecruitingPhase 2
Zinc and vitamin B3 supplement for IPF
This trial tests whether adding zinc and nicotinamide riboside (a vitamin B3-like supplement) to standard IPF treatment can help improve lung function. It is for people with IPF who are already seeing a lung doctor and live in certain states.
Los Angeles, CaliforniaAges 50 years+ - NCT05732051RecruitingPhase 2
Nicotinamide riboside to protect the heart during breast cancer chemo
This trial tests whether nicotinamide riboside can help prevent heart problems caused by a common breast-cancer chemotherapy (anthracyclines). If you’re eligible, you’ll be followed to see how your heart is doing during treatment.
Lørenskog, AkershusAges 18 years+ - NCT05275738Recruiting
Nicotinamide treatment for glaucoma progression
This trial studies whether nicotinamide (a form of vitamin B3/niacin) can slow or affect glaucoma progression. You may be eligible if you have newly diagnosed, untreated glaucoma or if you have treated glaucoma with measurable visual field changes.
StockholmAges 18 years+ - NCT05740722RecruitingPhase 2
Nicotinamide riboside for progressive multiple sclerosis
This Phase 2 trial studies whether a vitamin-like supplement called nicotinamide riboside can slow or improve disability in progressive multiple sclerosis. It may help people whose symptoms have been steadily getting worse over the last 2 years.
BergenAges 18–65 - NCT07741071RecruitingPhase 2
Vitamin B3 supplement for early Alzheimer's disease
This study tests whether a daily supplement (nicotinamide riboside, a form of vitamin B3) can slow the progression of early Alzheimer's disease over two years. It is a randomized, double-blind trial, meaning half the participants will get the supplement and half will get a placebo (a pill with no active ingredient), and neither you nor the doctors will know which you are getting.
BergenAges 50–85 - NCT06640309RecruitingPhase 2
Nicotinamide for rheumatoid arthritis: a clinical trial
This trial tests if taking a vitamin B3 supplement (nicotinamide) can improve outcomes for people with rheumatoid arthritis. Researchers want to see if adding this over-the-counter vitamin to your usual arthritis medicines helps reduce disease activity.
CairoAges 18–65 - NCT07579429RecruitingPhase 2
Nicotinamide Riboside Supplement for MDS
This trial tests whether a supplement called nicotinamide riboside can help people with a blood disorder called MDS (myelodysplastic syndrome) or early warning signs of it. The supplement is meant to support your bone marrow's ability to make healthy blood cells.
Aurora, ColoradoAges 18 years+ - NCT07563322Recruiting
Nicotinamide Riboside for Combined Pulmonary Hypertension
This study tests whether nicotinamide riboside (a B-vitamin supplement) can help people with combined pulmonary hypertension—a condition where blood pressure in the lungs is too high. The researchers want to understand how this supplement affects the body's energy metabolism and whether it might reduce symptoms and improve heart function.
Nashville, TennesseeAges 18–85 - NCT06208527RecruitingPhase 2
Nicotinamide Riboside for Frailty in Older Adults
This trial tests whether a daily supplement called nicotinamide riboside can help older adults who feel weak or frail to get stronger and more energetic. It lasts for several months and involves simple tests like a walking test and memory checks.
Bergen, VestlandAges 75 years+ - NCT06853743RecruitingPhase 2
Study of nicotinamide riboside for Huntington's disease
This trial tests if a vitamin B3-like supplement, nicotinamide riboside, can help people with early to mid-stage Huntington's disease. You will be randomly assigned to take the supplement or a placebo to see if it slows the disease.
OsloAges 18–80 - NCT06882096RecruitingPhase 1
How the body processes NAD+ boosters in healthy adults
This study looks at how the body uses NAD+ precursors (nutrients that help cells produce energy) after taking them by mouth. Healthy volunteers will help researchers understand how these supplements are processed, which may guide future treatments for aging and disease.
Boston, MassachusettsAges 18 years+ - NCT07144527Recruiting
NMN supplement for exercise in healthy older adults
This trial tests whether a supplement called nicotinamide mononucleotide (NMN) can help healthy adults aged 60 to 80 improve their exercise tolerance. You'll take the supplement and do supervised cycling sessions to see if it boosts your stamina.
Beverly Hills, CaliforniaAges 60–80 - NCT07024966Recruiting
A study of supplements for oxidative stress in runners
This study tests whether a combination of three natural supplements (pterostilbene, silybin, and nicotinamide riboside) can reduce exercise-related oxidative stress in amateur runners. If it works, these supplements might help protect your body's cells during intense running.
Reus, TarragonaAges 18–50 - NCT06971224RecruitingPhase 2
Can a vitamin B3 supplement improve sleep?
This study tests whether a daily supplement called nicotinamide riboside (a form of vitamin B3) can improve sleep quality in healthy adults. If you are between 40 and 60 years old, have normal sleep, and are not taking sleep aids, you may be able to join.
BergenAges 40–60 - NCT06425042Recruiting
Nicotinamide riboside with exercise for healthy aging
This study tests whether a daily supplement called nicotinamide riboside (a form of vitamin B3), combined with a supervised exercise program, can help promote healthy aging and improve how well your body functions. You would take the supplement or a placebo for 12 weeks while doing light to moderate exercise.
Santiago, Santiago MetropolitanAges 60–80 - NCT05243290Recruiting
Nicotinamide riboside for Gulf War illness
This trial studies whether nicotinamide riboside (a vitamin-like substance related to vitamin B3) can improve symptoms of Gulf War illness in eligible Gulf War veterans. If you qualify, you may be asked to take the supplement and complete symptom assessments during the study.
Fort Lauderdale, FloridaAges 47–70 - NCT06587945RecruitingPhase 4
Nicotinamide riboside for retinal detachment repair
This trial tests if taking a daily supplement called nicotinamide riboside after retinal detachment surgery can help the eye heal better and see more clearly. It is for people who had a specific type of retinal detachment and have already had cataract surgery.
East Melbourne, VictoriaAges 18 years+ - NCT06280482RecruitingPhase 1
Nicotinamide Riboside for Moyamoya in Smooth Muscle Dysfunction
This trial tests a vitamin B3 supplement called nicotinamide riboside (NR) to see if it can help people with Smooth Muscle Dysfunction Syndrome (SMDS) who have a specific gene mutation. The goal is to improve blood flow problems in the brain (moyamoya-like disease) caused by the condition.
Houston, TexasAges 1 year+ - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06032923RecruitingPhase 1/Phase 2
Does vitamin B3 boost help lupus symptoms?
This study tests whether a form of vitamin B3, called nicotinamide riboside, can improve immune function and reduce inflammation in women with mild to moderate lupus. It may help understand if boosting NAD+ levels offers a new way to manage the disease.
Bethesda, MarylandAges 18–120 - NCT05955924RecruitingPhase 3
Nicotinamide to prevent skin cancer after organ transplant
This trial tests nicotinamide (a vitamin-like medicine) to help prevent new keratinocyte skin cancers in people who have had a kidney, liver, heart, or lung transplant. It may lower the chance of developing new skin tumors while you continue your usual transplant anti-rejection medicines.
Calgary, AlbertaAges 18 years+
What Nicotinamide is being studied for
Conditions with recruiting Nicotinamide studies.
Common questions
- Are there clinical trials studying Nicotinamide?
- Yes. Clin2 currently lists 51 recruiting studies that include Nicotinamide, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Nicotinamide trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Nicotinamide an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Nicotinamide or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.