Test drug treatment for pituitary Cushing disease
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This Phase 2 trial tests fimepinostat (a targeted cancer-style drug) to help control Cushing disease caused by a pituitary tumor. It’s mainly for adults whose Cushing is confirmed to come from the pituitary and who meet safety and medication-washout rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be an adult (age 18 or older)
- Have confirmed pituitary-source Cushing disease (not another cause of Cushing)
- Have evidence that the condition is still active (high urine cortisol on 3 test days, and supporting hormone/imaging findings)
- Have a pituitary tumor that is seen on MRI or confirmed by a specialist test (IPSS)
- Be able to finish any prior Cushing medicines “washout” before screening (timing depends on the drug)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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