Clinical trials
Cushing Disease clinical trials
Below are recruiting cushing disease clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03774446RecruitingPhase 2
Seliciclib trial for Cushing disease from a pituitary tumor
This Phase 2 study tests seliciclib (also called R-roscovitine) in people with Cushing disease caused by a pituitary tumor and ongoing high cortisol levels. It may help reduce excess cortisol production in those whose Cushing disease has not fully gone away or has come back after standard treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT03831958Recruiting
Follow-up study of children cured of Cushing disease
This study checks long-term health in people who were treated successfully for Cushing disease when they were under 21. It also collects information from family members to study genetic links to pituitary tumors.
Bethesda, MarylandAges 2–90 - NCT05971758RecruitingPhase 2
Test drug treatment for pituitary Cushing disease
This Phase 2 trial tests fimepinostat (a targeted cancer-style drug) to help control Cushing disease caused by a pituitary tumor. It’s mainly for adults whose Cushing is confirmed to come from the pituitary and who meet safety and medication-washout rules.
Los Angeles, CaliforniaAges 18 years+ - NCT03364803Recruiting
Sharing treatment results for people with Cushing’s syndrome
This is a study that collects and reviews information about how people with Cushing’s syndrome (including some mild forms and certain “silent” tumors) are diagnosed and treated, and what outcomes they have. It may help researchers understand which treatments work best in different types of the condition.
Basking Ridge, New JerseyAges 14 years+ - NCT07460232RecruitingEarly Phase 1
PET scan for Cushing disease pituitary adenomas
This study uses a special PET scan (FET PET/CT) to help find tiny pituitary tumors causing Cushing disease. The goal is to improve surgery planning so the tumor can be removed successfully.
Rochester, MinnesotaAges 18 years+ - NCT07108244Enrolling by invitation
Better brain scan for small pituitary tumors in Cushing's disease
This study tests a special type of brain scan (PET-MRI) to better find tiny pituitary tumors causing Cushing's disease. It may help people whose standard MRI didn't show a clear tumor.
Rotterdam, South HollandAges 18 years+ - NCT07603466Enrolling by invitationPhase 4
Two drugs combined to treat Cushing's disease
This trial tests whether taking two medications together—osilodrostat and cabergoline—can help control Cushing's disease by lowering excess cortisol levels. Cushing's disease is caused by a pituitary tumor that makes too much of a hormone called ACTH, which drives cortisol overproduction.
BasraAges 18–70 - NCT06471829RecruitingPhase 2
Study of Lu AG13909 for adults with Cushing's disease
This study tests a new medicine called Lu AG13909 for adults with Cushing's disease caused by a pituitary tumor. It aims to see if the medicine can lower cortisol levels and help control the disease.
Ann Arbor, MichiganAges 18–70 - NCT07335315Recruiting
Ultrasound with contrast for pituitary tumor surgery
This trial is testing a special ultrasound during surgery to see if it can help doctors find pituitary tumors, especially in Cushing's disease. The contrast agent is a tiny bubble that makes the tumor show up better on ultrasound.
Rochester, MinnesotaAges Any age - NCT07703683Recruiting
Muscle health in metabolic and hormone diseases
This trial looks at how muscle health is affected by metabolic or hormone disorders, aiming to find better markers for muscle loss called sarcopenia.
Woluwe-Saint-Pierre - Sint-Pieters-WoluweAges 18 years+ - NCT06573723Recruiting
Rare disease registry at Hospital Italiano
This study collects information from patients with certain rare diseases to better understand them. If you have one of these conditions and receive care at Hospital Italiano de Buenos Aires, you may be able to join.
Buenos Aires, Buenos AiresAges Any age - NCT05881005Recruiting
NAC for fatty liver in people with active Cushing’s
This study tests whether NAC (a supplement/medicine) can improve liver health in adults who have active Cushing’s syndrome and fatty liver disease. It may help if your excess stress hormone levels are affecting your liver.
AngersAges 18 years+ - NCT00001595Recruiting
Study of pituitary tumors and related hormone gland disorders
This research study investigates tumors and disorders of the pituitary gland (a small gland that controls many body hormones) and related areas of the brain. You may qualify if you have a pituitary tumor or disorder, or if you have a family history of these conditions.
Bethesda, MarylandAges 2–70 - NCT07463625Recruiting
PET scan for finding ACTH-secreting pituitary tumors
This trial tests a special PET scan using a tracer called FET to locate tiny ACTH-producing pituitary tumors (microadenomas) causing Cushing's disease. It might help guide surgery by identifying exactly where the tumor is in the gland.
BronAges 18 years+ - NCT06050057Recruiting
Surgery for adrenal disease: Standard vs. robotic-assisted approach
This study compares two types of minimally invasive surgery for removing an adrenal gland: laparoscopic (small incisions, using a camera) and robot-assisted (using a robotic arm). It aims to see which approach may be better for recovery and safety.
OlomoucAges 18 years+ - NCT04569591Recruiting
Using DDAVP with PET scans to find pituitary tumor source
This study tests whether giving DDAVP before a PET scan can help doctors better locate the pituitary problem in people with Cushing disease. It may help confirm where the ACTH-producing tumor is so surgery can be planned more accurately.
Bethesda, MarylandAges 8–99 - NCT03474237Enrolling by invitation
Study following people newly diagnosed with adrenal conditions
This study follows adults with a new adrenal diagnosis to learn how adrenal diseases behave over time. It may help doctors better understand these conditions and improve future care.
SeoulAges 19 years+ - NCT06635629RecruitingPhase 2
Desmopressin test for ACTH-dependent Cushing syndrome
This trial studies how well a desmopressin stimulation test works to diagnose ACTH-dependent Cushing syndrome. It compares results from people with possible or recurrent Cushing syndrome and healthy volunteers.
Bethesda, MarylandAges 18–70 - NCT02019706RecruitingPhase 2
PET/CT scans to find the cause of ectopic Cushing syndrome
This trial tests several special imaging scans to help doctors locate the source of hormone overproduction in ectopic Cushing syndrome. It may help confirm where the problem is so treatment can be better targeted.
Bethesda, MarylandAges 18–80
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Cushing Disease trials by city
Studies with a site in or near these metro areas.
Cushing Disease trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for cushing disease?
- Yes. Clin2 currently lists 19 recruiting cushing disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cushing disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cushing disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.