Metabolomics study during ECT for depression
Part of Mental health clinical trials.
This study measures changes in your blood and/or body chemistry while you receive electroconvulsive therapy (ECT) for a severe mood episode. The goal is to understand biological signals related to ECT and treatment-resistant depression, which may help improve future care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You currently have a major depressive episode (a severe depression lasting enough to meet DSM-5 criteria).
- You have a diagnosis of major depression or bipolar disorder.
- Your depression severity score (MADRS) is above 22.
- Your depression is current and your care team has decided ECT is an appropriate treatment.
- You have tried two antidepressants at effective doses for at least 6 weeks each, and they did not work well enough.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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