Clot retrieval for smaller brain artery strokes
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests if removing clots from smaller arteries in the brain (not the main ones) helps people who had a stroke and can't get standard clot-busting medicine. It compares clot removal to usual care for strokes caused by these medium-sized vessel blockages.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older and had a stroke caused by a blockage in a medium artery (not the largest ones)
- You cannot get the standard clot-busting medicine (tPA) or it didn't work for you
- Your stroke symptoms are disabling (you have trouble speaking, moving your arm or leg, etc.)
- The clot must be in a specific type of artery (like M2, M3, A1–A3, or P1–P3 segments) and the artery is between 1.5 and 2.5 mm wide
- You weren't disabled before the stroke (you could do daily activities without help)
- Brain scans show that the area of brain at risk is larger than the already damaged area, and the core damage is less than 50 cc
- You can be treated within 12 hours from when you were last seen well
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
This trial compares a procedure to remove a blood clot from a brain artery (endovascular therapy) with standard medicines alone, for people who had a large-vessel stroke more than 24 hours ago (up to 30 days). It aims to see if the procedure can still help improve recovery even after this longer time window, especially if symptoms are fluctuating or worsening.
This study tests whether removing a clot from a medium-sized brain artery using a minimally invasive procedure (catheter) can improve recovery after a stroke. It's for people who cannot get standard clot-busting medicine and whose stroke started within the last day.
This trial tests a procedure called endovascular thrombectomy (clot removal through a catheter) for people with very large strokes. It aims to see if removing the clot can help even when a large part of the brain is already damaged.
This trial tests a procedure to remove a large blood clot in the brain (mechanical thrombectomy) for people who have a very large stroke. It aims to see if removing the clot can improve recovery, even for those with severe strokes.
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
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