Expanding clot removal for medium vessel strokes
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older
- You must be able to have the clot removal procedure started within 2 hours of your last brain scan
- You must have a blockage in a large or medium brain blood vessel (confirmed by imaging)
- Your stroke symptoms must score between 0-5 (mild) OR 8 or higher on the NIHSS stroke scale
- You must not have certain conditions like active infection in the blood, severe bleeding risk, or terminal illness
- You must not have a known pregnancy or severe brain swelling or hemorrhage
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if removing clots from smaller arteries in the brain (not the main ones) helps people who had a stroke and can't get standard clot-busting medicine. It compares clot removal to usual care for strokes caused by these medium-sized vessel blockages.
This trial compares a procedure to remove a blood clot from a brain artery (endovascular therapy) with standard medicines alone, for people who had a large-vessel stroke more than 24 hours ago (up to 30 days). It aims to see if the procedure can still help improve recovery even after this longer time window, especially if symptoms are fluctuating or worsening.
This trial tests endovascular therapy (a procedure to remove a clot through a tube in an artery) versus medical management for people with a severe stroke due to a blockage in the back part of the brain (basilar artery) and a large area of brain damage. The goal is to see if the procedure improves outcomes compared to medication alone.
This trial tests a procedure called endovascular thrombectomy (clot removal through a catheter) for people with very large strokes. It aims to see if removing the clot can help even when a large part of the brain is already damaged.
This trial tests a procedure to remove a large blood clot in the brain (mechanical thrombectomy) for people who have a very large stroke. It aims to see if removing the clot can improve recovery, even for those with severe strokes.
This study tests whether removing a clot from a medium-sized brain artery using a minimally invasive procedure (catheter) can improve recovery after a stroke. It's for people who cannot get standard clot-busting medicine and whose stroke started within the last day.
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