Bivalirudin during angioplasty for high-risk heart plaques
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a blood thinner called bivalirudin, given during a procedure to open blocked heart arteries (PCI), helps blood flow better in the tiny vessels of the heart afterward. It is for people with a recent unstable heart condition and a high-risk plaque seen on a CT scan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have either a type of heart attack called NSTEMI or unstable angina (chest pain that comes on suddenly).
- You are scheduled to have a procedure to open blocked arteries (called PCI or angioplasty).
- A CT scan of your heart in the last 3 months showed a high-risk plaque (a dangerous fatty deposit in an artery).
- You do not have active bleeding, a bleeding disorder, severe liver or kidney disease, or a recent stent in the same artery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if bivalirudin is a safe and effective blood thinner for people on ECMO, a machine that helps your heart and lungs. You may be eligible if you need this therapy and have no past reactions to similar medicines.
This trial compares treatments for heart patients who have a dangerous, but not fully blocking, fatty plaque in their arteries. It aims to see if treating these plaques with a stent or balloon can prevent future heart problems.
This study compares two blood-thinning medicines used during a heart procedure (PCI) after you've already received clot-busting drugs. The goal is to see which one helps prevent more blockages and complications.
This study compares two blood thinners, bivalirudin and heparin, given during a heart procedure to open blocked arteries (PCI). It aims to find which one is safer for people at high risk of bleeding.
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This trial looks at whether a “drug-coated balloon” used during a heart procedure (PCI) is safer or better for people who are at higher risk of bleeding while on blood thinners. It may help reduce complications around the time of the procedure in people like you.
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