Clinical trials
Coronary Microvascular Dysfunction clinical trials
Below are recruiting coronary microvascular dysfunction clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02582021Recruiting
Study of treatments and imaging in women with angina or HFpEF
This trial studies how heart disease affects the heart using heart imaging, and looks at people with chest pain/angina or heart failure with preserved pumping strength (HFpEF). It may help doctors better understand what’s driving symptoms and how best to evaluate these conditions.
Los Angeles, CaliforniaAges 18 years+ - NCT06681896Recruiting
Exercise rehabilitation for heart microvessel disease
This trial tests a supervised exercise program for people with chest pain caused by tiny heart blood vessel problems (microvascular dysfunction). It aims to see if exercise can improve symptoms and heart function.
BathAges 18 years+ - NCT02301663Recruiting
Stress test study of heart blood-flow issues in adults
This study tests a new kind of stress test to understand how small blood-vessel heart problems relate to heart relaxation problems in people with angina (chest pain) but no blocked arteries. It may help doctors learn better ways to diagnose and guide treatment for these conditions.
Los Angeles, CaliforniaAges 18–60 - NCT06503640Recruiting
Microvascular dysfunction in angina patients
This study tests if chest pain with clear arteries is caused by tiny heart vessel problems. It may help find better treatments for patients whose arteries look normal on angiograms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05960474Recruiting
Study registry for coronary microvascular disease
This trial is a registry, meaning it mainly collects information about people with coronary microvascular disease. It may help researchers better understand the condition and how it affects daily health and treatment needs.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05984537RecruitingPhase 4
Bivalirudin during angioplasty for high-risk heart plaques
This study tests whether a blood thinner called bivalirudin, given during a procedure to open blocked heart arteries (PCI), helps blood flow better in the tiny vessels of the heart afterward. It is for people with a recent unstable heart condition and a high-risk plaque seen on a CT scan.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04674449Recruiting
Tests a targeted plan for people with chest pain from heart artery disease
This study aims to match people with angina (chest pain from heart artery problems) to the most helpful treatment plan based on their test results. It’s done around the time doctors are planning an invasive heart scan to look at the coronary arteries.
CorkAges 18 years+ - NCT05272618Recruiting
Testing heart vessel dysfunction after a heart attack
This trial looks at how to assess small blood-vessel (microvascular) problems in people who had a heart attack but whose main heart arteries are not blocked. It may help doctors better find what’s driving symptoms and choose the right tests and treatments.
Gwangju, GwangjuAges 19 years+ - NCT05841199Recruiting
Study heart blood flow during fast heart rates
This study measures how well blood flows through the heart when the heart rate is increased during a heart procedure. It may help doctors better understand coronary (heart artery) blood flow and how to guide treatment when you need angiography or angioplasty.
LondonAges 18 years+ - NCT06076551Recruiting
Sex differences in small blood vessel problems of the heart
This study looks at how small blood vessels in the heart work differently in men and women who have chest pain but no major blockages in their main heart arteries. The goal is to better understand and treat these smaller vessel issues.
SeoulAges 20–80 - NCT06089031Recruiting
Belgian registry for coronary function testing
This study collects information from people having tests to check how well the blood vessels in the heart work. It helps doctors learn more about these tests and improve care for future patients.
Deurne, AntwerpAges 18 years+ - NCT06125392Recruiting
New Definition for Small Heart Vessel Disease
This trial studies a condition where small heart vessels don't work well. It looks at new ways to define this problem using a special test that measures pressure and blood flow in a heart artery.
Mainz, Rhineland-PalatinateAges 18–90 - NCT06376630Recruiting
Esmolol for heart protection during heart attack
This study tests if giving a fast-acting heart medication (esmolol) early through an IV can protect the heart muscle during a heart attack. It may help patients who cannot receive a standard treatment due to certain risks.
MoscowAges 18 years+ - NCT06393478Recruiting
Southeastern Europe Microcirculation Registry
This study is collecting information about how well the tiny blood vessels in the heart work in people with chest pain. It helps doctors learn more about microcirculation problems and may lead to better treatments.
RijekaAges 18 years+ - NCT06588244Recruiting
Registry for chest pain with open arteries
This study is looking at people who have chest pain or shortness of breath but whose heart arteries look fairly open on an angiogram. It aims to understand why they have symptoms and how to improve care. You may qualify if you're having a coronary angiogram and it shows no major blockages.
Naples, ItalyAges Any age - NCT06597851Recruiting
Insulin resistance and heart artery health: a study for chest pain patients
This study looks at how insulin resistance affects tiny heart arteries in people who have chest pain and signs of heart stress on tests, but do not have major blockages in their heart arteries. It aims to understand why some people have heart symptoms even when their main arteries appear clear.
Verona, VRAges 18 years+ - NCT06600178RecruitingPhase 1
Heart medication for women with chest pain and small vessel disease
This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.
Charlottesville, VirginiaAges 18 years+ - NCT06606821RecruitingPhase 4
Tirzepatide for heart health in people with overweight or obesity
This trial tests the weight‑loss medication tirzepatide (Mounjaro) in people who are overweight or have obesity and have stable coronary artery disease. The goal is to see if tirzepatide can reduce dangerous fatty plaque in heart arteries.
CopenhagenAges 18 years+ - NCT06795035Recruiting
Coronary microvascular testing after heart attack
This study tests a way to measure tiny blood vessels in the heart after a major heart attack (STEMI) using a special catheter with salt water. The goal is to see if this test helps doctors understand how well your heart is healing.
Cleveland, OhioAges 18 years+ - NCT07103317Recruiting
Understanding heart blood flow in chest pain without blockages
This study looks at people who have chest pain but don't have major blockages in their heart arteries. It aims to understand how the tiny blood vessels and artery spasms might be causing symptoms, using special heart tests.
Prague, Česká RepublikaAges 18 years+ - NCT07222683Recruiting
How kidney transplant affects heart blood vessel health
This study looks at how receiving a kidney transplant changes the health of small blood vessels in the heart. It may help people with advanced kidney disease understand the benefits of transplant on their heart health.
Boston, MassachusettsAges 18 years+ - NCT02180178Recruiting
Heart catheter registry for slow coronary blood flow
This study builds a database of people who are having a coronary angiography (a heart blood-vessel X-ray test). It aims to better understand conditions like slow blood flow in the heart’s small vessels and may help improve how these conditions are diagnosed and treated.
MainzAges Any age - NCT06898541Enrolling by invitation
A device to treat chest pain from small heart artery disease
This trial tests a device called the Coronary Sinus Reducer for people with chest pain caused by problems in the small arteries of the heart. The device is placed in a vein near the heart to improve blood flow and reduce symptoms.
RotterdamAges 40 years+ - NCT06332131Enrolling by invitation
Heart blood vessel effects of immunotherapy in breast and lung cancer
This trial studies whether immunotherapy drugs (called immune checkpoint inhibitors) affect the small blood vessels of the heart. If you have breast cancer or lung cancer and are starting a specific treatment plan, you may be asked to have a special heart scan before and during therapy.
Philadelphia, PennsylvaniaAges 18 years+
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Coronary Microvascular Dysfunction trials by city
Studies with a site in or near these metro areas.
Coronary Microvascular Dysfunction trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for coronary microvascular dysfunction?
- Yes. Clin2 currently lists 51 recruiting coronary microvascular dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary microvascular dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary microvascular dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.