Clopidogrel vs warfarin to prevent a second APS stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation, Immune system & allergy clinical trials.
This study compares two types of blood thinners — clopidogrel (an antiplatelet) and warfarin — to prevent another stroke in people with antiphospholipid syndrome (APS). It aims to find which medicine works better for people who have already had a stroke related to APS.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 19 years or older.
- You have had a stroke, mini-stroke, or a brief loss of vision in one eye due to a clot.
- You have been diagnosed with antiphospholipid syndrome (APS), a condition that makes your blood clot too easily.
- You do not have a very high-risk antibody profile called 'triple positive'.
- You do not have lupus (systemic lupus erythematosus).
- You are able to stop taking your current blood thinner or antiplatelet medicine (if you are taking one).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study keeps a registry to follow people with antiphospholipid syndrome (APS) who have had arterial blood clots (like stroke). It collects information about the treatment approach your clinician chooses to see how different antithrombotic regimens may perform and be tolerated.
This trial tests a combination of two blood thinners (antiplatelet drugs) to see if they work better than one in people who had a mild stroke caused by a narrowed artery in the brain. If you had a recent first stroke and are otherwise healthy, you may be able to join.
This trial tests if ticagrelor or cilostazol is better at preventing a second stroke in people who have had their first mild to moderate ischemic stroke. It aims to find which treatment works best within the first 24 hours of symptoms.
This trial tests a combination of blood thinners to prevent another stroke in people who have a narrowed artery in the brain. It compares standard treatment to a combination of low-dose blood thinners to see if this approach works better to prevent future strokes.
This study keeps an international registry of people with antiphospholipid syndrome (APS) who are taking direct oral blood thinners. It may help doctors better understand how APS patients do over time and improve future care, even if you’re not asked to change treatment.
This trial tests whether combining aspirin with a second antiplatelet drug (ticagrelor or clopidogrel) helps prevent another stroke after a mild stroke or TIA. It might lower your risk of having another event.
Hear when a new Antiphospholipid Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.