Clin2
NCT06001658Possibly a fitRecruiting

Chemo plus immunotherapy before and after surgery for bile duct cancer

Billiary Track Cancer

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a combination of chemotherapy (gemcitabine and cisplatin) and an immunotherapy drug (pembrolizumab) given before and after surgery for people with bile duct or gallbladder cancer that can be removed. The goal is to see if this approach helps prevent the cancer from coming back.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
27 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have been diagnosed with a bile duct or gallbladder cancer that can be surgically removed.
  • You are 18 years or older.
  • You are in generally good health (able to do daily activities without significant assistance).
  • You have not had prior chemotherapy or immunotherapy for this cancer.
  • You do not have active autoimmune disease or an organ transplant.
  • Women who can become children and men with partners who can become pregnant must agree to use birth control during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06037655Not yet recruiting· Phase 2
Chemo plus immunotherapy before surgery for bile duct cancer

This trial tests a combination of chemotherapy, an immunotherapy drug (adebrelimab), and a drug to boost white blood cells (mecapegfilgrastim) before surgery for people with biliary tract cancer. The goal is to see if this approach can shrink the tumor enough to make surgery possible.

NCT06903273Not yet recruiting· Phase 2
Combination chemo-immunotherapy before surgery for high-risk bile duct cancer

This trial tests a combination of immunotherapy (tislelizumab) and chemotherapy (gemcitabine, cisplatin, S-1) given before surgery for patients with bile duct cancer that is high-risk for return or has come back within 6 months after a prior surgery. The goal is to see if this treatment can improve outcomes.

Tainan
NCT06181032Recruiting· Phase 1
Immunotherapy and chemo combo before surgery for bile duct cancer

This trial tests a combination of an immunotherapy (adebrelimab), a targeted therapy (apatinib), and two chemotherapy drugs (gemcitabine and cisplatin) given before surgery for biliary tract cancers that are removable but at high risk of coming back. The goal is to see if this approach helps shrink the tumor and improve outcomes after surgery.

Fuzhou, Fujian
NCT07291063Recruiting
Immunotherapy plus chemo for advanced bile duct or gallbladder cancer

This trial tests combining immunotherapy (anti-PD-1/PD-L1 antibodies) with standard chemotherapy (gemcitabine and cisplatin) for people with advanced bile duct or gallbladder cancer that can't be removed by surgery. The goal is to see if this combination works better than chemo alone.

Shanghai, Shanghai Municipality
NCT06569225Not yet recruiting· Phase 2
Chemo plus immunotherapy for resectable bile duct cancer

This trial tests a combination of chemotherapy drugs (gemcitabine, cisplatin, nab-paclitaxel) with an immunotherapy (rilvegostomig) before and after surgery for intrahepatic cholangiocarcinoma that can be completely removed. It aims to see if this approach improves outcomes.

Toronto, Ontario
NCT07569679Recruiting· Phase 2
Combination Chemotherapy and Immunotherapy for Biliary Tract Cancer

This trial tests a combination of chemotherapy drugs given directly into the liver, combined with two immunotherapy/targeted therapy drugs, for people with advanced biliary tract cancer (cancer of the bile ducts or gallbladder). The goal is to shrink tumors and improve survival in patients who have not received prior chemotherapy.

Xi'an, Shaanxi

Hear when a new Billiary Track Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.