Psilocybin for cancer pain study
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial tests whether psilocybin (a psychedelic drug) can help with severe cancer pain. You may qualify if your pain is high despite strong medications and you are willing to be monitored closely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your cancer is advanced and not likely to be cured or controlled.
- Your average pain is at least a 4 out of 10 in the past week.
- You are taking strong pain medicine (opioids) equal to 200 mg of morphine or more each day.
- You have seen a palliative care doctor at Dana-Farber or Massachusetts General Hospital in the last 3 months.
- You are able to swallow pills and have a support person who can be contacted if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether psilocybin (with support and therapy) can reduce anxiety in people with advanced cancer. It may help with distress and quality of life, while the study team monitors safety closely.
This study tests whether psilocybin (a compound found in certain mushrooms) can help reduce chronic nerve pain that has not responded well to standard medications. You will receive study treatment plus psychotherapy to see if it improves your pain.
This trial tests whether a drug called psilocybin, given with therapy, can help people with advanced cancer who are feeling anxious or depressed. You must have a stable cancer and be willing to travel to Houston for treatment.
This trial tests whether psilocybin (a psychedelic substance) can help manage pain after a trauma surgery for people with a history of opioid addiction. You'd receive a single dose in the hospital and be monitored for 8 hours.
This study tests whether psilocybin (a hallucinogen) combined with psychological support can help reduce feelings of hopelessness and loss of meaning in people with advanced cancer. It aims to see if this treatment can improve emotional well-being and quality of life.
This trial tests if psilocybin can help veterans with chronic pain who also smoke cigarettes. You will take psilocybin in a controlled setting to see if it reduces pain and helps with smoking.
Hear when a new Opioid-Related Disorders trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.