Testing a new drug for advanced ER-positive breast cancer
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests an experimental oral drug (FWD1802) for women with a specific type of advanced breast cancer (ER-positive, HER2-negative) that has stopped responding to hormone therapy. It looks at whether the drug can slow or stop cancer growth, especially if you have an ESR1 mutation.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be a woman aged 18 or older.
- You must have advanced (locally advanced or metastatic) breast cancer that is ER-positive and HER2-negative.
- You must be past menopause or agree to take medication to suppress ovarian function.
- Your cancer must have progressed after at least one prior hormone therapy (like tamoxifen or an aromatase inhibitor) for advanced disease.
- You may have had up to 2 prior chemotherapy treatments for advanced breast cancer, but no more.
- For the Phase II part, a blood test must show that your tumor has an ESR1 mutation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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