Nose spray medicine for pain during eye exams in preemies
Treatments studied
Part of Brain & nervous system, Eyes & vision, Genetic & congenital, Pain clinical trials.
This study tests a nose spray medicine (dexmedetomidine) to help reduce pain and discomfort in premature babies who need eye exams for retinopathy of prematurity (a condition that can affect vision). The goal is to see if the spray works better than the usual care for calming babies during the exam.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby was born before 31 weeks of pregnancy, or weighed less than 1500 grams (about 3.3 pounds) at birth.
- You (the parent or guardian) must sign a consent form agreeing to let your baby participate.
- Your baby is not on a breathing machine (ventilator) right now.
- Your baby does not have any major birth defects or genetic conditions.
- Your baby has not received any sedative (calming) medicine in the last 5 days.
- The eye exam is for routine retinopathy of prematurity screening, not for another reason.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a medication given through the nose (dexmedetomidine) can help children stay calmer when waking up from eye-muscle surgery. Some children get very agitated or upset when coming out of anesthesia, and this medication might help prevent that.
This trial tests a nasal spray that helps you feel calm and relaxed before anesthesia for your surgery. It may be an option for people having general anesthesia or other types of anesthesia, and the study checks if it is safe and works well.
This trial tests whether a medicine called midazolam, given as nose drops, helps reduce stress and pain in premature babies during the routine eye exam for retinopathy of prematurity (an eye problem in premature babies). If your baby is eligible, they may receive this medicine during the exam to make it more comfortable.
This trial tests a medicine called dexmedetomidine to keep premature babies calm and comfortable while they are on a breathing machine. It may help reduce pain and stress for your baby during this difficult time.
This study tests a new way to give a nasal spray of fentanyl (a strong painkiller) to premature babies before their routine eye exams for ROP. It aims to see if this medicine reduces pain and discomfort during the exam better than current standard care.
This study tests different methods to manage pain and comfort in premature infants during their first eye exam for retinopathy of prematurity. It may help find ways to make the exam less stressful for babies.
Hear when a new Retinopathy of Prematurity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.