Dexmedetomidine for premature babies on a breathing machine

This study compares two sedative medicines, dexmedetomidine and midazolam, to see which one helps preterm babies on a ventilator breathe on their own sooner. Your baby may be eligible if they were born very early and need medicine to relax while on the breathing machine.

This study tests whether a sedative medication called dexmedetomidine can reduce confusion and delirium in children who need mechanical ventilation (breathing machines) in the intensive care unit. Researchers want to see if it works better and safer than standard sedatives.

This trial tests if a drug called dexmedetomidine works better than morphine to manage pain and discomfort in newborns who are undergoing cooling therapy after a brain injury at birth. It may help your baby be more comfortable during treatment.

This study tests a nose spray medicine (dexmedetomidine) to help reduce pain and discomfort in premature babies who need eye exams for retinopathy of prematurity (a condition that can affect vision). The goal is to see if the spray works better than the usual care for calming babies during the exam.

This early-phase trial compares two calming medicines to help critically ill, agitated patients come off the breathing machine earlier and more safely. Your participation would help doctors learn which medicine works better for agitation during the weaning process.

This trial tests whether adding a sedative called dexmedetomidine to non-invasive ventilation (a breathing mask) helps adults who are agitated or uncomfortable while on the mask. It aims to improve comfort and avoid the need for a breathing tube.