Prednisone pills for bone LCH in children and teens
Treatments studied
Part of Blood & lymphatic, Lungs & breathing clinical trials.
This trial tests whether taking a steroid pill (prednisone) by mouth can help children and teenagers with bone-only LCH. It is for people who do not need surgery and can swallow pills.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with Langerhans cell histiocytosis (LCH) in your bones.
- Your LCH is only in your bones (not in other organs like your liver, spleen, or brain).
- You do not need surgery for your bone LCH.
- You can swallow tablets (pills) without help.
- You have not taken steroid medicine (like prednisone) in the last 2 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is testing a new targeted pill (luvometinib) alone or with another drug (cytarabine) for people with Langerhans cell histiocytosis that needs whole-body treatment. The goal is to see if the new approach can shrink or control the disease.
This trial tests a new drug called Luvometinib added to a standard chemotherapy regimen for children with Langerhans cell histiocytosis that affects multiple parts of the body. The goal is to see if the combination works better than the standard treatment alone.
This phase 3 study compares two treatment plans for Langerhans cell histiocytosis (LCH): vinblastine plus prednisone versus cytarabine alone. It aims to find which approach works better and is safer for children and young adults with LCH that needs medicines.
This trial tests the drug luvometinib for children with a specific type of bone disease called Langerhans cell histiocytosis (LCH). It may help kids who have not been treated before and whose LCH is in certain bones, including the head, face, or spine.
This study is looking for adults with Langerhans cell histiocytosis (LCH) and also for adults with certain lung conditions (like cystic lung disease or emphysema) or healthy smokers to act as controls. The goal is to find biomarkers (signs in the body) that can help doctors diagnose LCH, predict how it will progress, and see how well treatment is working.
This trial tests a combination of two drugs for children and teens with Langerhans cell histiocytosis (LCH) that has not responded to standard treatments or has come back after treatment. The goal is to see if the drugs can shrink lesions and improve symptoms.
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