Early cholesterol-lowering injection after stroke from narrowed arteries
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving a cholesterol-lowering injection (called a PCSK9 inhibitor) early after a stroke helps improve recovery and lowers cholesterol. It is for people whose stroke is caused by narrowed arteries, not by heart problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a recent stroke (within the last 7 days) that was not caused by a heart clot.
- You are 19 years old or older.
- You have significant narrowing of a major artery in your neck or brain due to plaque build-up.
- Your stroke symptoms are mild to moderate (not severe disability).
- You have not had bleeding in the brain, a brain tumor, or a brain infection.
- You are not pregnant or breastfeeding, and do not have severe liver or kidney disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a cholesterol-lowering drug (called a PCSK9 inhibitor) can help people who had a stroke and a procedure to clear a blocked vessel. It aims to see if the drug reduces the risk of another stroke or improves recovery.
This trial tests whether quickly starting an aggressive cholesterol-lowering treatment after a stroke improves recovery. It is for people who are about to have a procedure to remove a large blood clot from their brain.
This study tests whether starting a cholesterol-lowering injection (a PCSK9 inhibitor) early after a heart attack can slow or shrink the buildup of plaque in other heart arteries that are not the one that was stented. If you have two other arteries with mild blockages, this treatment might help prevent future heart problems.
This trial tests whether a cholesterol-lowering medication called evolocumab (a PCSK9 inhibitor) can help people recover better after a specific type of stroke caused by clogged arteries. The study checks if lowering cholesterol further than usual statins do improves stroke outcomes and is safe.
This trial tests whether a cholesterol-lowering medicine (called a PCSK9 inhibitor) can help people who recently had a stroke caused by a narrowed artery in the brain. The goal is to see if it reduces the risk of another stroke or helps recovery.
This trial tests whether adding an intensive cholesterol-lowering drug (called a PCSK9 inhibitor) to standard care can reduce the risk of another stroke or heart attack in people who recently had a stroke from narrowed brain or neck arteries. It is a high-dose approach designed to rapidly lower cholesterol and may offer extra protection for those with high Lp(a).
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