Cholesterol-lowering drug after stroke treatment
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether a cholesterol-lowering drug (called a PCSK9 inhibitor) can help people who had a stroke and a procedure to clear a blocked vessel. It aims to see if the drug reduces the risk of another stroke or improves recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a stroke caused by a blocked blood vessel in the front part of your brain.
- The blockage was severe, and you had a procedure to remove it (endovascular therapy) recently.
- Your 'bad' cholesterol (LDL) is above a certain level (more than 1.8 mmol/L).
- You have not had major bleeding or bleeding in the brain in the past 3 months.
- You are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a cholesterol-lowering medication called evolocumab (a PCSK9 inhibitor) can help people recover better after a specific type of stroke caused by clogged arteries. The study checks if lowering cholesterol further than usual statins do improves stroke outcomes and is safe.
This trial tests whether giving a cholesterol-lowering injection (called a PCSK9 inhibitor) early after a stroke helps improve recovery and lowers cholesterol. It is for people whose stroke is caused by narrowed arteries, not by heart problems.
This trial tests whether quickly starting an aggressive cholesterol-lowering treatment after a stroke improves recovery. It is for people who are about to have a procedure to remove a large blood clot from their brain.
This trial tests whether adding an intensive cholesterol-lowering drug (called a PCSK9 inhibitor) to standard care can reduce the risk of another stroke or heart attack in people who recently had a stroke from narrowed brain or neck arteries. It is a high-dose approach designed to rapidly lower cholesterol and may offer extra protection for those with high Lp(a).
This study tests whether a new injectable cholesterol-lowering drug (called a PCSK9 inhibitor) can help prevent further heart problems by making plaque in your arteries more stable and less likely to cause blocked vessels. It is for people who recently had a heart attack or unstable angina and already received a stent in the blocked artery.
This trial tests whether a cholesterol-lowering medicine (called a PCSK9 inhibitor) can help people who recently had a stroke caused by a narrowed artery in the brain. The goal is to see if it reduces the risk of another stroke or helps recovery.
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