Weaning from high-flow oxygen therapy in the ICU
Part of Lungs & breathing clinical trials.
This trial is testing a way to safely reduce high-flow oxygen therapy for patients in the ICU who have low oxygen levels. It might help find the right time to stop this treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult admitted to the ICU for sudden low oxygen levels (with a specific blood test result).
- You have been on high-flow oxygen therapy for at least 24 hours, with the flow at 50 liters per minute or more and oxygen concentration at 50% or higher.
- Your oxygen levels and breathing rate must be stable or improving in the last 6 hours before joining.
- You had a blood gas test (a blood draw from an artery) while on high-flow oxygen therapy within the last 24 hours.
- You are covered by social security and you or your family member can sign a consent form.
- You do not have severe COPD, a history of lung scarring, or heart-related fluid in the lungs as the main cause of your breathing problem.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a step-by-step plan to safely reduce and stop high-flow nasal cannula oxygen therapy in adults who are stable enough to start weaning. It may help you breathe on your own sooner.
This study looks at a scoring system (ROX Index) to help decide the best timing to place a breathing tube (intubate) for adults who are struggling to get enough oxygen while using nasal high-flow (NHF). The goal is to see if using this timing approach can improve care for acute lung failure in the ICU.
This study helps doctors predict which patients receiving high-flow oxygen through a nasal tube will need additional breathing support. Researchers use blood tests and clinical information to identify who might need a ventilator, allowing earlier interventions if needed.
This trial compares three ways of giving extra oxygen to people with low blood oxygen levels: a face mask with continuous pressure, a noninvasive ventilator, or high-flow oxygen through the nose. The goal is to see which method helps people avoid needing a breathing tube.
This trial tests a system that automatically adjusts oxygen levels for patients receiving high flow oxygen therapy. The goal is to see if it can keep oxygen levels in a safe range better than usual care.
This study tests whether using high-flow oxygen through a nasal cannula during the breathing tube placement can help keep oxygen levels stable in ICU patients who already have low oxygen. It compares this method to standard care.
Hear when a new Acute Hypoxemic Respiratory Failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.