Closing the loop on oxygen use during high flow therapy

This trial compares three ways of giving extra oxygen to people with low blood oxygen levels: a face mask with continuous pressure, a noninvasive ventilator, or high-flow oxygen through the nose. The goal is to see which method helps people avoid needing a breathing tube.

This trial is testing a way to safely reduce high-flow oxygen therapy for patients in the ICU who have low oxygen levels. It might help find the right time to stop this treatment.

This study helps doctors predict which patients receiving high-flow oxygen through a nasal tube will need additional breathing support. Researchers use blood tests and clinical information to identify who might need a ventilator, allowing earlier interventions if needed.

This study looks at a scoring system (ROX Index) to help decide the best timing to place a breathing tube (intubate) for adults who are struggling to get enough oxygen while using nasal high-flow (NHF). The goal is to see if using this timing approach can improve care for acute lung failure in the ICU.

This trial looks at how a test might help evaluate adults who come to the emergency room with a brand-new, sudden breathing problem that needs high-flow oxygen. It may help doctors identify what’s going on faster and guide care in the early hours.

This trial tests a closed-loop system that automatically adjusts the oxygen level in your breathing tube, aiming to keep your oxygen levels in a safe range with less need for manual changes. It may help if you are in the ICU, need a breathing machine, and have low blood oxygen despite receiving extra oxygen.