Pacing methods for heart failure with wide QRS
Part of Heart & circulation clinical trials.
This trial compares two ways to pace the heart in people with heart failure and a wide QRS (a sign the heart's electrical signals are slowed). The goal is to see which method better reduces the risks of death, heart failure hospitalization, or needing a heart transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have heart failure with a reduced ejection fraction (LVEF 35% or less) and a wide QRS (130 ms or more) due to left bundle branch block.
- Or you have a wide QRS of 150 ms or more with a reduced ejection fraction (35% or less) from a different cause.
- Or you need a pacemaker for a heart block and have a reduced ejection fraction (less than 40%).
- Or you have atrial fibrillation, a wide QRS of 130 ms or more, and a reduced ejection fraction (35% or less) with class III or IV symptoms, and a plan to ensure both sides of the heart are paced.
- You have not had a heart attack, unstable angina, or heart surgery in the last 3 months.
- You are not pregnant and not currently in another trial with an active treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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