Pacing to improve heart function study
Part of Heart & circulation clinical trials.
This study tests a new way to pace the heart to see if it can improve how well the heart pumps. It uses a special Abbott pacemaker to pace a part of the heart called the left bundle branch and adjust the timing to match your natural heart rhythm.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your doctor has approved you for a pacemaker that paces both the upper and lower chambers or for a special heart failure pacing device (CRT).
- You have a type of heart block called left bundle branch block (LBBB) or a delay in the heart's electrical signals (IVCD).
- Your natural heart electrical signal (QRS) is 130 milliseconds or longer.
- Your heart's own timing (PR interval) is 250 milliseconds or less.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial compares two types of pacing for people with permanent atrial fibrillation (AF) and a weak heart pump (ejection fraction less than 50%). It tests whether pacing the left bundle branch area works as well as or better than standard biventricular pacing to improve heart function.
This trial compares two types of heart pacing to see which improves outcomes for people with heart failure. It may help those who need pacing to better coordinate heartbeats and relieve symptoms.
This trial compares two types of “left-side” heart pacing to see which one works better in people with weak heart pumping. It may help guide the best pacing choice for improving heart function and symptoms.
This study uses MRI scans to see how different pacing methods affect your heart's performance. It may help doctors choose the best pacing for you if you need a pacemaker for certain heart block conditions.
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This trial tests a pacing approach designed to improve how the heart beats in some people with heart failure and a specific heart rhythm pattern on ECG. If you already need a device (CRT-D) based on your results, the study may help see whether this pacing correction improves outcomes.
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