Comparing pill and IV medicine to reduce bleeding during heart surgery
Treatments studied
Part of Heart & circulation clinical trials.
This study compares two ways of giving a medicine called tranexamic acid — as a pill or through an IV — to see which works better at reducing bleeding during heart bypass surgery. If you are having heart surgery without a heart-lung machine, this trial may help you recover with less bleeding.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older and scheduled for elective (non-emergency) heart bypass surgery that is planned to be done without a heart-lung machine.
- Your doctor plans to use tranexamic acid (a medicine to reduce bleeding) as part of your routine care, and you can take it either by mouth or through an IV.
- You must be able to give written consent and attend follow-up visits while in the hospital and at 30 days after surgery.
- Your kidney function must be good enough (not on dialysis and with an estimated filtration rate above 30), and you must not have any allergy or other reason that makes tranexamic acid unsafe for you.
- You must not be pregnant or breastfeeding, and you must not be participating in another clinical trial that could interfere with this study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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