Comparing treatments for leg artery blockages with severe calcium
Part of Heart & circulation, Hormones & metabolism clinical trials.
This trial tests a special preparation method (breaking up calcium) plus a Supera stent versus standard preparation plus stenting for people with severe calcium buildup and long blockages in the thigh or behind-the-knee artery. It aims to see which approach works better for opening the artery and keeping it open.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have leg pain when walking (Rutherford 2-5), not at rest or with minor tissue loss
- You have a new or re-narrowed blockage in the thigh or behind-the-knee artery that is at least 10 cm long and severely calcified
- You have not had a stent placed in the same blockage before, or if you did, it is at least 3 cm away
- At least one artery below the knee to the ankle is open and healthy
- You are willing to attend follow-up visits and not pregnant or breastfeeding
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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