Immune response after donated heart valve replacement
Part of Immune system & allergy, Lungs & breathing clinical trials.
This study looks at how your immune system reacts to a donated heart valve (called a homograft) used to replace your pulmonary valve. It will help doctors understand why some people develop antibodies that might affect the valve, which could improve future care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 14 years or older.
- You must be scheduled to receive a pulmonary valve replacement using a donated valve (homograft).
- You cannot have had a blood transfusion during your surgery or within the last 6 months.
- You cannot have had any HLA antibodies (immune proteins that might attack the donor valve) before this surgery.
- You cannot be pregnant or have given birth in the last 6 months.
- Your surgery must be planned (not an emergency), and you (or your parents/guardians) must sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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