Blood pressure medicine study for people with repaired coarctation of the aorta
Treatments studied
Part of Genetic & congenital, Heart & circulation clinical trials.
This trial tests a type of blood pressure medicine (an angiotensin-II receptor blocker) to see if it can help prevent changes in the heart's structure. It is for people who have had surgery for a coarctation of the aorta and now have mild to moderate high blood pressure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have had surgery to repair a coarctation of the aorta (a narrowing of the main artery from the heart).
- You have mild to moderate high blood pressure (systolic reading between 100 and 139 mm Hg).
- You are not currently taking a beta blocker (a type of heart-slowing blood pressure medicine).
- You have not taken any blood pressure medications in the past year.
- You do not have severe heart valve disease, coronary artery disease, low kidney function, or high potassium levels.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at whether a supervised exercise program can improve fitness and quality of life in adults who were born with a narrowed aorta (coarctation) and had surgery to fix it as a baby or child. It aims to see if exercise is safe and helpful for heart health and daily energy, without placing extra strain on the repaired area.
This trial tests a treatment to help people with a mildly enlarged ascending aorta. It aims to slow down growth and prevent future heart problems.
This study tests whether angiotensin receptor blocker (ARB) blood pressure medication helps people with mild to moderate aortic stenosis (a narrowing of the heart’s main valve). It looks at safety and whether the treatment offers benefit for your heart and blood flow.
This study checks if people with repaired coarctation of the aorta who develop high blood pressure only during exercise have any damage to their blood vessels or organs. It aims to understand how exercise affects long-term health after aortic repair.
This trial tests if the drug losartan can help the heart recover better after surgery to replace a leaky aortic valve. It may reduce strain on the heart and improve long-term outcomes.
This trial uses a special blood pressure monitor (CART BP Pro) to help guide treatment for people whose blood pressure stays high despite standard care. You may qualify if your blood pressure is still too high even with medication.
Hear when a new Coarctation of Aorta trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.