Losartan after aortic valve surgery for severe leakage
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if the drug losartan can help the heart recover better after surgery to replace a leaky aortic valve. It may reduce strain on the heart and improve long-term outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have had surgery to replace your aortic valve because it was leaking severely.
- You do not have other major heart valve problems.
- You do not have blocked heart arteries causing heart muscle damage.
- Your surgery was not done during cardiogenic shock or because of a heart infection.
- You do not have advanced kidney disease, very low blood pressure, high potassium, or allergy to losartan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a blood pressure medication called valsartan can reduce leaking in the mitral valve (a valve in your heart) caused by an enlarged left chamber. The goal is to see if this medication can improve heart function and reduce symptoms without needing surgery.
This trial tests if losartan, a blood pressure medication, can improve healing and recovery after surgery for a multi-ligament knee injury. Taking losartan for 30 days after surgery may reduce stiffness and help you get back to your normal activities sooner.
This trial studies how well the heart's main pumping chamber (left ventricle) recovers after surgery to fix a leaky aortic valve. It is for people who also have a leaky mitral valve and an enlarged left ventricle, and who are having their first planned valve surgery.
This study tests whether losartan, a blood pressure medicine, can prevent excessive scar tissue (arthrofibrosis) after a total knee replacement. Participants receive losartan or a placebo for 6 months after surgery to see if it improves knee motion and reduces stiffness.
This trial tests a type of blood pressure medicine (an angiotensin-II receptor blocker) to see if it can help prevent changes in the heart's structure. It is for people who have had surgery for a coarctation of the aorta and now have mild to moderate high blood pressure.
This study tests when to start two heart-protective medications (ARNI and SGLT2 inhibitors) after you've had surgery to fix a valve problem or blocked heart arteries. Researchers want to see if waiting a bit before starting these drugs helps your heart recover better.
Hear when a new Heart Valve Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.