Clot Removal for Worsening Mild Stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation, Injuries & trauma clinical trials.
This trial tests whether emergency clot removal (endovascular therapy) can help people whose mild stroke gets worse within a week. It's for those who have a blockage in a large brain artery and enough healthy brain tissue to save.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You had a mild stroke (NIHSS score less than 6) that then got worse within 7 days
- Imaging (CTA or MRA) shows a blockage in a large artery in your brain (internal carotid artery or M1 segment of middle cerebral artery)
- Your brain scan shows a certain amount of salvageable brain tissue and not too much damage (core infarct <50ml, mismatch ratio ≥1.8, mismatch volume >15ml)
- You are not pregnant, do not have uncontrolled high blood pressure or blood sugar, and do not have a bleeding disorder or recent major bleeding/surgery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
This trial tests whether removing a blood clot from a large brain artery is better than standard medical care for people who have a mild stroke (NIHSS score 2-5) but still have symptoms like trouble speaking, weakness, or confusion. It is for patients who can be treated within 24 hours of their last known well time.
This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
This trial tests whether removing a blood clot from a large brain artery (using a catheter through the groin) can help people with mild stroke symptoms. It is for patients whose stroke started within the last 24 hours and who have a blockage in the front part of the brain's blood supply.
This trial tests a procedure called endovascular thrombectomy (clot removal through a catheter) for people with very large strokes. It aims to see if removing the clot can help even when a large part of the brain is already damaged.
This trial tests if removing clots from smaller arteries in the brain (not the main ones) helps people who had a stroke and can't get standard clot-busting medicine. It compares clot removal to usual care for strokes caused by these medium-sized vessel blockages.
Hear when a new Stroke, Ischemic trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.