DVRd treatment for newly diagnosed double-hit myeloma
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This trial tests a combination of four drugs (daratumumab, bortezomib, lenalidomide, and dexamethasone) for people newly diagnosed with a high-risk form of multiple myeloma called double-hit myeloma. It aims to see if this drug combo can improve outcomes for those with two or more high-risk genetic changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 69 years old.
- You have been newly diagnosed with multiple myeloma and have at least two high-risk genetic abnormalities (like certain chromosome changes).
- You have not yet had any chemotherapy for your myeloma, except maybe a short course of steroids.
- Your kidney, liver, and blood cell counts are within certain safe ranges.
- You are willing to use effective birth control if you could become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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