Natural Killer Cells After Half-Matched Stem Cell Transplant for High-Risk AML
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This study tests a new way to prevent leukemia from returning after a half-matched stem cell transplant. It uses specially activated natural killer cells to attack remaining cancer cells. This may help people with high-risk or relapsed AML who have few other options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have acute myeloid leukemia (AML) that is in remission (no visible cancer cells) or, if not in remission, must meet specific high-risk criteria like certain genetic changes.
- If you've had a previous stem cell transplant, you may still qualify under certain conditions.
- You must be 40 years old or younger.
- You need to have adequate organ function (liver, kidneys, heart, lungs).
- You must have a related donor who is a half-match (haploidentical) and meets health requirements.
- You must not have active graft-versus-host disease or other uncontrolled illnesses.
- You must agree to use contraception if applicable, and not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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