NMDA treatment for depression that did not improve
Treatments studied
Part of Mental health clinical trials.
This trial studies an NMDA-based treatment for people with major depressive disorder who did not respond to at least one antidepressant. It may help by changing brain signaling linked to depression symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of major depressive disorder (MDD) based on DSM-5 criteria
- You tried at least one antidepressant at the right dose for long enough and it didn’t help
- Your depression score must be at least 18 on the 17-question Hamilton Depression scale
- Your current depression treatment plan must be stable (not changed for at least 8 weeks), or you must be off antidepressants for at least 2 weeks if you stopped them yourself after prior failures
- You can sign consent and follow the study plan
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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