Pola-R2 for older, less fit adults with new DLBCL
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a combination of three drugs (pola, Rituxan, and lenalidomide) for older adults (70+) with a common type of lymphoma (DLBCL) who are not well enough for standard chemotherapy. The goal is to see if this gentler treatment works well for patients who are less fit.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 70 years old or older and your doctor has said you are not fit or frail.
- You have a type of lymphoma called diffuse large B-cell lymphoma and have not had any cancer treatment before (steroid pills alone are okay).
- Your organs and bone marrow are working well enough, as confirmed by your doctor.
- You do not have another cancer besides lymphoma.
- You do not have an active hepatitis B infection.
- You are stable and do not have serious heart, liver, kidney, or active infection problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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