A Study of Four Drugs for Older Adults with DLBCL
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a combination of four medications (pomalidomide, rituximab, orelabrutinib, and polatuzumab vedotin) for newly diagnosed, elderly patients with diffuse large B-cell lymphoma (DLBCL) who cannot tolerate standard treatments. It aims to see if this combination is effective and safe for older adults.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 70 years old or older and have been diagnosed with DLBCL that has not been treated yet.
- You have at least one tumor that can be seen on imaging and is at least 1.5 cm in size.
- Your heart, liver, kidneys, and lungs are working well enough as determined by certain tests.
- You have adequate blood cell counts (like red blood cells, platelets, and white blood cells).
- You are willing to use birth control if needed, and you can understand and sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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