Blood clots after heart closure device: re-treatment study
Part of Heart & circulation clinical trials.
This study looks at people who have a blood clot that keeps coming back or won't go away after having a device implanted to close a part of the heart called the left atrial appendage. The goal is to learn more about these clots and how to manage them better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have been diagnosed with a probable or definite blood clot (thrombus) on or in a device that was placed to close the left atrial appendage of your heart.
- The clot must have been detected by a special ultrasound (transesophageal echocardiography) or a heart CT scan.
- You must be able to understand and sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares a procedure that blocks a heart blood-choke point (the left atrial appendage) versus taking blood thinners by mouth. It is for people with atrial fibrillation who have had a brain bleed and may be safer avoiding long-term blood thinners.
This study looks at long-term outcomes after LAA closure (a procedure to reduce stroke risk) by reviewing CT scans of the device. It aims to learn if blood flow around the device affects healing and future health.
This study is for people who had a stroke despite taking blood thinners for atrial fibrillation. It tests if adding a procedure to close the left atrial appendage (a small pouch in the heart) to your blood thinner is better than just taking the blood thinner alone to prevent another stroke.
This trial compares a heart device that can help prevent blood clots in the heart (called LAAO) versus long-term blood thinners for people who have atrial fibrillation and recently had a stent placed. It aims to see which approach better prevents stroke and related blood-clot problems while keeping side effects manageable.
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
This trial tests a device that closes off a small pouch in the heart where blood clots can form in people with atrial fibrillation. This may help reduce the risk of stroke without needing long-term blood thinners.
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