Left atrial appendage closure to prevent stroke in AF
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether closing a heart pocket called the left atrial appendage can lower future stroke or other clot-related events in people with atrial fibrillation. It’s mainly for people who have had a prior clot-related event or are at higher risk but may not be good candidates for long-term blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and can understand the study and sign consent
- You have atrial fibrillation that is not from a heart valve problem (non-valvular AF)
- You have had a prior atrial-fibrillation related embolic event (like a stroke/TIA caused by AF)
- One of these fits you: high bleeding risk, cannot take long-term blood thinners, have trouble taking blood thinners, or elevated stroke risk
- Your clinician says you need left atrial appendage closure (LAA closure) and it’s suitable for you
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a device and procedure to close off a small pouch in the heart (left atrial appendage) where blood clots can form in people with atrial fibrillation. The goal is to reduce the risk of stroke, possibly lowering the need for long-term blood thinners.
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