Left atrial appendage device vs blood thinners after stent
Treatments studied
Part of Heart & circulation clinical trials.
This trial compares a heart device that can help prevent blood clots in the heart (called LAAO) versus long-term blood thinners for people who have atrial fibrillation and recently had a stent placed. It aims to see which approach better prevents stroke and related blood-clot problems while keeping side effects manageable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a successful heart stent procedure (PCI) for unstable angina or stable chest-pain symptoms
- You have atrial fibrillation that is not caused by a damaged heart valve
- You also have at least one added risk factor like heart failure, high blood pressure, age 65+, diabetes, or a prior stroke/TIA/blood clot
- Your doctor says you can take a long-term blood thinner called a NOAC
- You can understand the study, sign consent, and follow all medication and visit instructions
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at whether a lower-dose blood thinner works as well as the usual recommended anti-clot treatment after a procedure that closes off the heart’s left atrial appendage. It may help reduce bleeding risk while still preventing dangerous blood clots.
This trial compares which two medicines work best after a device closes off a part of the heart called the left atrial appendage. It may help reduce stroke risk while balancing bleeding risk after your procedure.
This trial tests whether patients who receive a special device to close a hole in the heart (to prevent stroke from irregular heartbeat) can safely take fewer blood-thinning medications afterward. The study compares taking a standard blood thinner for 3 months versus taking aspirin only, to see which approach works best with fewer bleeding risks.
This trial studies whether closing off part of the heart (the left atrial appendage) can prevent stroke as well as long-term newer blood-thinner pills. It may help people with atrial fibrillation who recently had a stroke or a warning stroke (TIA).
This trial tests a new device (LAmbre Plus) that closes off a small pouch in the heart (left atrial appendage) to reduce stroke risk in people with AFib who cannot take blood thinners long-term. The procedure is an alternative to daily medication.
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
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