Closing the left atrial appendage with the LAmbre Plus device
Part of Heart & circulation clinical trials.
This trial tests a device that closes off a small pouch in the heart where blood clots can form in people with atrial fibrillation. This may help reduce the risk of stroke without needing long-term blood thinners.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have atrial fibrillation (irregular heartbeat) that is not caused by a heart valve problem
- You have a higher risk of stroke and are currently recommended to take blood thinners
- You are able to take warfarin (a blood thinner) for a short time, but you and your doctor have reasons to avoid long-term blood thinners
- Your doctor has confirmed that your heart's structure is suitable for this device
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a procedure to close off a small pouch in the heart called the left atrial appendage, which is a common source of blood clots in people with atrial fibrillation. The goal is to lower your stroke risk without needing to take blood thinners long-term.
This study compares two ways of closing a small pouch in the heart (the left atrial appendage) to help prevent strokes in people with atrial fibrillation (an irregular heartbeat). One method is less invasive, and the study aims to see if it is as safe and effective as the standard approach.
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