Daptomycin before joint replacement surgery for infection
Part of Bones, joints & muscles, Infections clinical trials.
This trial tests whether a strong antibiotic called daptomycin, given before surgery, can prevent infection when you get a new joint put in after treating a joint infection. It's for people whose infection was caused by hard-to-treat bacteria like MRSA.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- Your joint infection is caused by a gram-positive bacteria, like MRSA (a type of staph).
- You are scheduled to have a second surgery to put a new joint in after the first infection treatment.
- You are not allergic to Cefazolin, Daptomycin, or Vancomycin.
- You do not have advanced chronic kidney disease (creatinine clearance below 30).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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