Diuretics vs. blood pressure meds for HeartLogic alerts
Treatments studied
Part of Heart & circulation clinical trials.
This trial compares two treatments—diuretics (water pills) and a blood pressure medication called sacubitril/valsartan—to see which works better when your heart device sends an alert. It's for people with a Boston Scientific heart device that has HeartLogic alerting turned on.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a Boston Scientific heart device that can use the HeartLogic alert feature.
- You do not have any of the conditions that make it unsafe to take sacubitril/valsartan (like past allergic reaction to ACE inhibitors or ARBs, very low blood pressure, kidney artery narrowing or kidney failure, high potassium, severe liver disease, or pregnancy).
- You do not have any conditions that make it unsafe to take diuretics (water pills).
- Your resting blood pressure (systolic) is above 105.
- Your kidney function is good enough (eGFR over 25) and you are not on chronic dialysis.
- You are not currently having worsening heart failure symptoms (like shortness of breath or tiredness).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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