Comparing two blood pressure medicines for heart health
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether a combination of two blood pressure drugs (sacubitril/valsartan) is better than one drug alone (valsartan) at improving heart function in people with high blood pressure. It may help reduce strain on the heart's upper chambers.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 65 years old.
- You have high blood pressure and take medicine for it, with a systolic reading of 150 or higher at the start.
- Your heart's pumping ability is normal (over 50% on an echo).
- Your left atrium (a heart chamber) is enlarged, measured by a specific index on an echo.
- You do not have severe high blood pressure (over 180), kidney disease, high potassium, or are pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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