Clin2
NCT06227221Worth exploringNot yet recruiting

Sorafenib for preserving insulin in new type 1 diabetes

Type 1 Diabetes

Treatments studied

Part of Hormones & metabolism, Immune system & allergy clinical trials.

This trial tests whether the drug sorafenib can help preserve the body's ability to make insulin in people recently diagnosed with type 1 diabetes. It may slow the progression of the disease and reduce the need for insulin injections.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
10 people
Ages
18 years to 60 years
Study type
Interventional

Who can take part

  • You must be between 18 and 60 years old.
  • You must have been diagnosed with type 1 diabetes within the last year.
  • You must test positive for at least one diabetes-related antibody (such as GAD, IA-2, or ZnT8).
  • Your pancreas must still be making some insulin, as shown by a C-peptide level greater than 200 pmol/L.
  • If you are of childbearing age, you must agree to use effective birth control during the study.
  • You must not have serious health conditions like active infections, heart disease, or significant kidney or liver problems.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07187531Recruiting· Phase 2
Testing a new drug to preserve insulin production in type 1 diabetes

This study tests a new drug called SAB-142, which aims to stop the immune system from attacking insulin-making cells in type 1 diabetes. It may help preserve your body's ability to make insulin. The trial will check if the drug is safe and effective.

San Francisco, California
NCT06524960Recruiting· Phase 1/Phase 2
Denosumab for Preserving Insulin in Type 1 Diabetes

This study tests if denosumab, a drug normally used for bone health, can help preserve your body's own insulin production in type 1 diabetes. It might slow the loss of insulin-making cells, helping you maintain better blood sugar control over time.

Birmingham, Alabama
NCT07594145Not yet recruiting· Phase 2
New treatments for heart and kidney problems in type 1 diabetes

This study tests new treatments for people with long-standing type 1 diabetes who also have early signs of heart or kidney disease. The goal is to see if these treatments can help protect the heart and kidneys.

Ann Arbor, Michigan
NCT07493122Not yet recruiting· Phase 1
Study of a new immune therapy for type 1 diabetes

This trial tests an investigational drug that may help preserve the body's ability to make insulin in people with type 1 diabetes. It aims to slow the progression of the disease and reduce the need for insulin injections.

NCT06082063Recruiting· Phase 3
Reducing heart disease risk in type 1 diabetes

This trial tests a combination of treatments to lower the risk of heart disease and kidney problems in people with type 1 diabetes who already have some complications or higher risk. If you qualify, you will receive extra care aimed at preventing heart attacks, strokes, and kidney failure.

Copenhagen
NCT05153070Recruiting· Phase 2
Cyclosporine then low-dose immune therapy for new type 1 diabetes

This Phase 2 study tests whether starting with cyclosporine and then giving low-dose IL-2 can better protect the body’s insulin-producing function after type 1 diabetes is diagnosed. It’s meant for people diagnosed very recently who have specific diabetes-related immune markers.

Paris

Hear when a new Type 1 diabetes trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.