Brain energy and glutamate in schizophrenia
Part of Mental health clinical trials.
This study uses brain scans (MRI and PET) to look at energy use and a brain chemical called glutamate in people with schizophrenia. It compares healthy volunteers to those with well-controlled schizophrenia and those with hard-to-treat schizophrenia to understand the biology better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can be a healthy volunteer with no psychiatric history.
- Or you have schizophrenia that is well-controlled (in remission) and you take an antipsychotic like olanzapine, risperidone, quetiapine, amisulpride, aripiprazole, or paliperidone.
- Or you have treatment-resistant schizophrenia, you take clozapine or another listed antipsychotic, and your symptoms are moderate to severe.
- No diabetes or diabetic medication, no metal implants or electronic devices in your body, and no severe claustrophobia.
- Must be able to give informed consent and not be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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