Study of darifenacin for people with ALS
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests a medication called darifenacin (usually used for bladder problems) in people with ALS, to see if it is safe and if it might help slow the disease. If you join, you will take the study drug or a placebo and be closely monitored.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of ALS (either familial or sporadic).
- You must be 18 to 85 years old.
- Your ALS symptoms must have started less than 36 months ago.
- Your lung function must be at least 50% of expected (FVC ≥ 50%).
- You must be able to swallow tablets without crushing them.
- You must not have certain other conditions like liver disease, glaucoma, or severe allergies to this type of medication.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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