Clinical trials
Amyotrophic Lateral Sclerosis clinical trials
Below are recruiting amyotrophic lateral sclerosis clinical trials, each written for real people, not researchers. We’re tracking 185 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04454892Recruiting
Study of ALS symptoms and disease course
This study watches people with ALS over time to better understand how symptoms change and what features show up. It may help future care and treatments by improving doctors’ understanding of ALS’s natural course.
BeijingAges Any age - NCT04008329Recruiting
Study of people with amyotrophic lateral sclerosis
This study follows people living with amyotrophic lateral sclerosis (ALS) over time. It may help researchers better understand ALS and track changes that could guide future treatments.
Fuzhou, FujianAges Any age - NCT04885374Recruiting
ALS patient registry for people using traditional Chinese medicine
This trial is a registry that collects information from adults with ALS who are using traditional Chinese medicine. It may help researchers better understand ALS and how traditional treatments are used alongside standard care.
BeijingAges 18 years+ - NCT03217396Recruiting
Study blood and MRI markers in people with multiple sclerosis
This study looks for signs of “synapse damage” in multiple sclerosis using blood tests and brain imaging (MRI). The goal is to find biomarkers that may help better understand MS and how it changes over time.
Pozzilli, IserniaAges 18–65 - NCT06344260RecruitingPhase 2
Neural stem cell therapy for ALS: a phase 2 trial
This trial tests whether injecting neural stem cells into the spine can slow down ALS. It is for people with rapidly progressing ALS who have good lung function and a caregiver to help with visits.
San Giovanni Rotondo, FoggiaAges 18–65 - NCT07798700Recruiting
Biofluid research for brain and movement disorders
This study collects blood, spinal fluid, and other samples from people with brain or movement disorders, their family members, and healthy volunteers. The goal is to find better ways to diagnose and understand these conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07726563Recruiting
Plasmapheresis for ALS with NRIP2 antibody
This trial tests whether a blood filtering treatment called plasmapheresis can help people with ALS who have a specific antibody (NRIP2) in their blood. It aims to see if removing this antibody can slow the disease and improve symptoms.
Taipei City, TaipeiAges 20 years+ - NCT07660614RecruitingPhase 1/Phase 2
Testing a new drug for people with ALS
This trial studies an experimental drug called LTX-002 for people with ALS. It aims to see if the drug is safe and can slow down the disease.
LübeckAges 18–75 - NCT06668649Recruiting
Polish fatigue scale study for MS, ALS, or stroke
This study tests a Polish version of a scale that measures how tired people feel. It's for people with MS, ALS, or stroke, or healthy volunteers.
Krakow, Lesser Poland VoivodeshipAges 18 years+ - NCT07571200RecruitingPhase 1
Study of LY4256984 for ALS in Previous Trial Participants
This is a follow-up study for people with ALS who have already completed another Eli Lilly ALS treatment trial. Researchers want to continue testing a new drug (LY4256984) in people who tolerated the previous treatment well.
LeuvenAges 18–80 - NCT07571174RecruitingPhase 1
ALS Study: Testing a New Drug in Spinal Fluid
This is a follow-up study for people with ALS (a disease affecting nerve and muscle control) who completed a previous trial called OWAA. Researchers want to test how a new experimental drug called LY4256984 affects the spinal fluid around your brain and spine, which may help them understand if it could slow disease progression.
LeuvenAges 18–80 - NCT07571486RecruitingPhase 1/Phase 2
Opening the blood-brain barrier for ALS treatment
This trial tests a device that temporarily opens the barrier between the blood and brain to see if it can help slow down ALS. It may allow treatments to reach the brain more effectively.
ParisAges 18–80 - NCT07543367Recruiting
Brain implant to restore arm movement in ALS
This study tests a surgically implanted brain-computer interface (BCI)—a device that reads signals directly from your brain to help control a computer cursor or robotic arm. It's designed for people with ALS whose arms are paralyzed and who haven't responded to standard treatments.
Jacksonville, FloridaAges 22 years+ - NCT07539662Enrolling by invitation
Cord Blood Stem Cell Transplant for ALS
This trial tests whether a transplant of special cells from donated umbilical cord blood can help slow or improve symptoms of ALS (amyotrophic lateral sclerosis, also called Lou Gehrig's disease). The cells may help repair nerve damage and reduce disease progression.
TianjinAges 35–50 - NCT06556394RecruitingPhase 1
Testing RAG-17 for ALS with SOD1 gene mutation
This trial tests a new drug, RAG-17, for people with ALS who have a specific SOD1 gene mutation. The goal is to see if it's safe and how it affects the body, which may help slow the disease.
BeijingAges 18 years+ - NCT07502677Recruiting
Can a sleep test detect breathing trouble in ALS?
This study tests a new wearable device called SleepImage to see how well it detects breathing problems during sleep in people with ALS. The goal is to catch early signs of respiratory failure before they become serious, helping doctors decide when to start breathing support.
LondonAges 18 years+ - NCT07491562Recruiting
Testing a neck brace for ALS-related neck weakness
This study tests a special neck brace (exoskeleton) designed to help people with ALS who have neck weakness. It will see if the device helps support your head and makes daily tasks easier.
Salt Lake City, UtahAges Any age - NCT07491484Recruiting
Physical function and quality of life in ALS patients
This trial measures how physical function affects daily life and well-being in people with ALS. It aims to understand how movement abilities impact patient-reported outcomes.
Salisbury, MarylandAges 18 years+ - NCT07478172Recruiting
Electrical muscle stimulation exercise for neuromuscular disease
This study tests whether whole-body electrical muscle stimulation (using small electrodes on the skin) can help adults with certain neuromuscular diseases exercise and improve muscle strength. It may be an option if you can stand for about 15 minutes at a time and have some muscle strength left.
Columbia, MissouriAges 18 years+ - NCT06820008Recruiting
Using smartphones to track physical changes in ALS
This study uses smartphone apps and digital tools to track physical changes in people with ALS. It aims to better understand how the disease affects daily function, which could help improve future care.
Dublin, DublinAges 18 years+ - NCT07414212RecruitingPhase 1/Phase 2
Testing EH-301 and NAC with Riluzole for ALS
This trial tests whether adding two supplements (EH-301 and N-acetylcysteine) to the standard ALS medicine Riluzole can help slow the disease. It is for people diagnosed with ALS within the last 18 months who still have good breathing and daily function.
San Sebastián, GuipuzcoaAges 18–75 - NCT07413718Recruiting
Breathing muscle training for ALS patients
This study tests whether a special breathing muscle training can help people with ALS maintain lung function. It may benefit patients diagnosed recently with spinal ALS and good breathing capacity.
Donostia / San Sebastian, GipuzkaAges 18–85 - NCT07401121RecruitingPhase 1
Study of CTx1000 for people with ALS
This trial tests a new drug, CTx1000, for people with ALS. It aims to see if the drug is safe and tolerable, and may offer a new treatment option.
Sydney, New South WalesAges 18–80 - NCT07369076RecruitingPhase 1/Phase 2
Testing NB-4746 for people with ALS
This study tests an investigational drug called NB-4746 for people with ALS. The goal is to see if it can slow the progression of the disease. It is for people diagnosed within the last couple of years who are still able to eat and breathe on their own.
Concord, New South WalesAges 18–80
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Amyotrophic Lateral Sclerosis trials by city
Studies with a site in or near these metro areas.
Amyotrophic Lateral Sclerosis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for amyotrophic lateral sclerosis?
- Yes. Clin2 currently lists 185 recruiting amyotrophic lateral sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a amyotrophic lateral sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a amyotrophic lateral sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.