Clin2
NCT06250972Possibly a fitRecruiting

Radiotherapy for advanced pancreatic cancer with normal CA19-9 after chemo

Pancreatic Adenocarcinoma

Part of Cancer clinical trials.

This trial tests whether giving radiotherapy to the pancreas can help people with advanced pancreatic cancer whose CA19-9 level has dropped to normal after chemotherapy. It's for patients whose cancer is still locally advanced (hasn't spread to distant organs).

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
210 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are between 18 and 80 years old.
  • You have advanced pancreatic adenocarcinoma that has not spread too far (locally advanced).
  • Your CA19-9 blood test level was high before chemotherapy and is now normal (37 or less).
  • You have not had radiotherapy before, and your cancer is not resistant to chemotherapy.
  • You are willing to use birth control if you could become pregnant or father a child.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06149689Recruiting· Phase 2
Chemo plus radiation for advanced pancreatic cancer with normal CA19-9

This trial tests whether giving a strong chemotherapy combination (mFOLFIRINOX) together with radiation therapy can help people with advanced pancreatic cancer who have normal CA19-9 levels. It aims to see if this approach is more effective for this specific group of patients.

Shanghai
NCT06217666Not yet recruiting· Phase 1
Radiation and immunotherapy for advanced pancreatic cancer

This trial tests whether giving targeted radiation (SBRT) followed by an experimental immunotherapy drug injected directly into the tumor is safe for people with locally advanced pancreatic cancer. It aims to shrink the tumor and help your immune system fight it.

Rochester, New York
NCT07126158Recruiting· Phase 2
Radiation plus targeted drugs for advanced pancreatic cancer

This trial tests a combination of targeted radiation and two oral drugs (defactinib and avutometinib) for people with advanced pancreatic cancer that hasn't spread to distant organs. It may be an option if you've already had at least 2 months of chemo and your cancer is still locally advanced or borderline resectable.

St Louis, Missouri
NCT06026943Recruiting
Alpha radiation therapy for locally advanced pancreatic cancer

This trial tests a new treatment that uses tiny alpha radiation sources placed directly into the tumor to destroy cancer cells. It is for people with pancreatic cancer that has not spread but cannot be removed surgically, and who have already tried at least one type of chemotherapy or cannot take more chemo.

Verona
NCT06249321Recruiting· Phase 2
Chemo plus radiation for advanced pancreatic cancer with normal CA19-9

This trial tests a combination of chemotherapy (mFOLFIRINOX) and radiation therapy for people with advanced pancreatic cancer that has stopped responding to chemotherapy and whose CA19-9 tumor marker levels are normal. The goal is to see if this approach can help when standard treatments are no longer working.

Shanghai, Shanghai Municipality
NCT05191940Recruiting
Radiation for advanced pancreatic cancer you can’t remove by surgery

This trial studies how well radiation therapy works for pancreatic cancer that is locally advanced (near important blood vessels) and cannot be removed with surgery. It may help shrink or control the cancer when surgery isn’t an option.

Wiener Neustadt, Lower Austria

Hear when a new Pancreatic Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.