Radiation for advanced pancreatic cancer you can’t remove by surgery
Treatments studied
Part of Cancer, Digestive system, Hormones & metabolism clinical trials.
This trial studies how well radiation therapy works for pancreatic cancer that is locally advanced (near important blood vessels) and cannot be removed with surgery. It may help shrink or control the cancer when surgery isn’t an option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have pancreatic cancer confirmed by biopsy or cancer cells; sometimes imaging plus a blood test called CA 19-9 can be enough
- Your cancer is locally advanced and not removable by curative surgery (for example, it involves key nearby vessels or major arteries)
- There’s no spread to distant organs (no distant metastasis)
- You’re 18 or older and well enough to handle treatment (Karnofsky score 70 or higher)
- Your tumor is not growing into the stomach or duodenum
- You can consent, and you’re able to safely receive radiation (no pregnancy/breastfeeding, and no prior abdominal radiation)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a combination of targeted radiation and two oral drugs (defactinib and avutometinib) for people with advanced pancreatic cancer that hasn't spread to distant organs. It may be an option if you've already had at least 2 months of chemo and your cancer is still locally advanced or borderline resectable.
This trial tests whether combining targeted radiation with an at-home “tumor treating fields” device can better control locally advanced pancreatic cancer. It may help by attacking cancer cells in more than one way after prior chemotherapy.
This trial tests a very focused type of radiation (SBRT) for people with pancreatic cancer that hasn't spread to other organs but can't be removed with surgery. It may be an option if you are medically unable to have surgery or choose not to.
This trial tests proton radiation for people with pancreas cancer that cannot be fully removed by surgery (or who choose not to have surgery). It may help shrink or control the cancer using a treatment that aims to better target the tumor while limiting dose to nearby organs.
This trial tests a type of radiation that uses carbon ions to treat pancreatic cancer that can’t be removed with surgery but has not spread to distant organs. It may help shrink or control the tumor while limiting radiation side effects to nearby organs.
This trial tests whether giving radiotherapy to the pancreas can help people with advanced pancreatic cancer whose CA19-9 level has dropped to normal after chemotherapy. It's for patients whose cancer is still locally advanced (hasn't spread to distant organs).
Hear when a new Pancreas Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.