Lifestyle change and medication for metabolic syndrome
Part of Hormones & metabolism clinical trials.
This trial tests a lifestyle program combined with two medications (semaglutide and dapagliflozin) to help people with metabolic syndrome lose weight and improve their health. It may be an option if you are an adult with a BMI of 27 to 45 and have metabolic syndrome.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 20 and 65 years old
- Your body mass index (BMI) is between 27 and 45
- You have been told you have metabolic syndrome (a cluster of conditions like high blood sugar, high blood pressure, or unhealthy cholesterol)
- You do not have type 1 or type 2 diabetes that requires medication
- You are not currently taking weight-loss drugs or participating in a weight-loss program
- You can commit to the study for 3 years
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests weight loss methods in people with type 2 diabetes, high blood pressure, and excess weight. It aims to see if losing 15-20% of body weight can help people live longer and healthier.
This trial tests if empagliflozin, a medication typically used for diabetes, can help people with metabolic syndrome (a cluster of conditions like large waist size, high blood sugar, and high blood pressure). It may improve health and reduce the risk of heart disease.
This trial tests whether semaglutide, a drug used for diabetes and weight loss, can improve heart-related health in people with schizophrenia who also have metabolic syndrome (a cluster of conditions like high blood pressure, high blood sugar, and excess belly fat). If it works, it could lower the risk of heart disease and stroke.
This study compares different diets to see how they affect “arterial stiffness” (how hard the blood vessels are) in people with obesity who are starting semaglutide for weight management. It may help find a diet approach that improves heart and blood-vessel health while you use semaglutide.
This study tests if a medication called semaglutide can help people with obesity lose weight by changing the bacteria in their gut. You may be able to join if you have obesity, have tried to lose weight before, and are generally healthy.
This study tests two different medicines (empagliflozin or semaglutide) added to your usual insulin to see if they help with blood sugar control and weight loss in people with type 1 diabetes who are overweight or have obesity. It may be a good fit if your diabetes is not well controlled with insulin injections alone.
Hear when a new Metabolic Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.