Probiotic treatment for Sjogren's syndrome
Part of Bones, joints & muscles, Eyes & vision, Immune system & allergy, Mouth & dental, Skin clinical trials.
This Phase 1 trial tests an experimental probiotic called R-2487 for people with Sjogren's syndrome. The goal is to see if it is safe and might help with symptoms like dry eyes and dry mouth.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a confirmed diagnosis of Sjogren's syndrome.
- You must be able to give your informed consent to join.
- If you take prednisone, your dose must be stable at 10 mg or less per day for at least 2 weeks.
- You must agree to use birth control during the study (if you or your partner can have children).
- You must not have other autoimmune diseases, active infections, or recent cancer.
- You must not have had a vaccine in the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares saliva, dental plaque, and stool samples from people with Sjogren's syndrome and healthy controls to understand how the mouth and gut bacteria differ. Participation is simple and involves providing samples during a dental visit and at home.
This study follows people who may have Sjögren’s disease to better understand how to diagnose it. If you have symptoms like dry eyes or dry mouth, this could help researchers confirm the diagnosis and learn what tests best explain it.
This trial tests an experimental drug called CLN-978, given as a shot under the skin, that helps your immune system target and destroy disease-causing B cells. It's for people with moderate to severe Sjögren's disease who haven't had success with other treatments.
This study tests the safety of a daily pill called Tofacitinib for adults with mild-to-moderate Sjögren's disease. It aims to see if this drug helps manage symptoms when other treatments haven't worked well.
This study tests a new medicine called ICP-488 for people with primary Sjögren's syndrome. It may help reduce symptoms like dry eyes and dry mouth by calming the immune system. The trial lasts about 48 weeks and includes regular check-ups.
This trial tests an experimental medication called ONO-4915 for people with primary Sjögren's disease. It aims to see if the drug can reduce dryness and other symptoms.
Hear when a new Sjogren's Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.