Vaccine immunotherapy for recurrent brain tumors or newly diagnosed DIPG
Part of Cancer clinical trials.
This trial tests a combination of a vaccine made from tumor cells and a drug that may boost the immune system's ability to fight brain tumors. It is for children and young adults with a recurrent high-grade glioma or a newly diagnosed diffuse midline glioma with a specific genetic marker (H3K27M).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of brain tumor called recurrent high-grade glioma or newly diagnosed DIPG with a specific mutation (H3K27M).
- You have finished radiation at least 14 days ago and are stable on a low dose of steroids for the last 2 weeks.
- You have adequate blood cell counts, liver and kidney function, and a performance score of at least 60%.
- You have not had certain cancer treatments, like targeted therapy or immunotherapy, in the last 28 days.
- You are not pregnant and agree to use effective birth control if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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